Noun
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the act of troubling or annoying someone
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something or someone that causes trouble
a source of unhappiness
"washing dishes was a nuisance before we got a dish washer"
"a bit of a bother"
"he's not a friend, he's an infliction"
- pain in the neck - pain in the ass -
an unpleasant person who is annoying or exasperating
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anger produced by some annoying irritation
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the psychological state of being irritated or annoyed