Noun
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the act of troubling or annoying someone
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unfriendly behavior that causes anger or resentment
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an uncomfortable feeling of mental painfulness or distress
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the neural or electrical arousal of an organ or muscle or gland
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(pathology) abnormal sensitivity to stimulation
"any food produced irritation of the stomach"
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a sudden outburst of anger
"his temper sparked like damp firewood"
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the psychological state of being irritated or annoyed